Offices For Lease in 4220 Duncan Ave, St. Louis

4220 Duncan Ave, St. Louis

4220 Duncan Ave, St. Louis, MO, 63110, United States

25 People

$ 708 to $ 10,146

150 ft2

CIC St. Louis opened its doors in October 2014 as the first expansion site for CIC outside of the original location in Cambridge, Massachusetts. Partnering with the growing Cortex district, we quickly established a location at 4240 Duncan Avenue and CIC@CET at the corner of Forest Park Park Avenue and Sarah Street. Our third location at 4220 Duncan Avenue opened in May of 2018. Combined, our three locations offer 160,000 sq ft of beautifully designed office space, coworking, wet lab facilities, event spaces, and shared amenities such as meeting rooms, phone booths, and fully stocked kitchens.We are a collaborative, inclusive, and value-adding center of gravity for entrepreneurship and innovation in St. Louis. We’re motivated by the energy of the incredible thinkers, creators, and doers in our community.

2 minute walk

Cortex Station

2 minute walk

Cortex Station

Building Summary

CIC (USA) has 4 private offices available to rent in 4220 Duncan Ave, St. Louis, MO, 63110, United States as at 14 November 2025. They have offices ranging in size from 1 to 25 people.

Building Facilities

Air Conditioning

High Speed Lift

After Hour Security

Bike Storage Available

Car Parking In Building

A Grade Building

Ground Floor Concierge

Disabled Access

Cafe/Retail in Building

5 Floors

Shower Facility Included

4 options in 4220 Duncan Ave, St. Louis

1 Person Private Office

$ 707 /month

was $ 707 /month

Details

3 Person Private Office

$ 1,688 /month

was $ 1,875 /month

Details

8 Person Private Office

$ 3,841 /month

was $ 4,519 /month

Details

25 Person Private Office

$ 10,148 /month

was $ 11,939 /month

Details

Location Map

4220 Duncan Ave, St. Louis, MO, 63110, United States

Explore the Vicinity

Trains

Cortex Station(2 mins walk)
Central West End Station(15 mins walk)

Buses

Cortex Station(2 mins walk)
4200 Forest Park EB Station(7 mins walk)

Airports

St Louis Airport (STL)(25 km drive)
Alton Airport (ALN)(48 km drive)

Cafes

Thomas Coffee(10 mins walk)
Kaldi's Coffee Roasting Co.(10 mins walk)
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Workspace Overview

Guided by the belief that stronger innovation ecosystems help to propel economic development and social impact, CIC has cofounded several mission-aligned organizations including Venture Café, CIC’s primary programming partner, and CIC Health, which has provided COVID-19 testing and vaccination services to millions of individuals, schools, and organizations.

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